SNW1 抗体
Quick Overview for SNW1 抗体 (ABIN7119203)
抗原
See all SNW1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- SNW domain containing 1
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亚型
- IgG
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anti-SNW Domain Containing 1 (SNW1) antibody
SNW1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNW Domain Containing 1 (SNW1) (AA 300-536) antibodySNW1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNW Domain Containing 1 (SNW1) (AA 464-497) antibodySNW1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB54232 unconjugated
anti-SNW Domain Containing 1 (SNW1) (AA 103-152) antibodySNW1 适用: 人, 小鼠, 犬, Cow, 马, Pig, 兔, 大鼠, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SNW Domain Containing 1 (SNW1) (N-Term) antibodySNW1 适用: 人, 小鼠, 犬, Cow, 马, Pig, 兔, 大鼠, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- SNW1 (SNW Domain Containing 1 (SNW1))
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别名
- SNW1
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背景
- Synonyms:SKIIP, SKIP Background:Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1-mediated transcriptional repression, and retinoid-X receptor(RXR)-and vitamin D receptor(VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds to multimerized forms of Notch intracellular domain(NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD. Proposed to be involved in transcriptional activation by EBV EBNA2 of CBF-1/RBPJ-repressed promoters. Is recruited by HIV-1 Tat to Tat:P-TEFb:TAR RNA complexes and is involved in Tat transcription by recruitment of MYC, MEN1 and TRRAP to the HIV promoter. Functions as a splicing factor in pre-mRNA splicing. Is required in the specific splicing of CDKN1A pre-mRNA, the function probbaly involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
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分子量
- 62-69 kDa
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基因ID
- 22938
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UniProt
- Q13573
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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