SMCR7L 抗体
Quick Overview for SMCR7L 抗体 (ABIN7119193)
抗原
See all SMCR7L 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- MIEF1 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- Smith-Magenis syndrome chromosome region, candidate 7-like
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:5000, IP: 1:500-1:5000, IF: 1:10-1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))
-
别名
- MIEF1
-
背景
-
Synonyms: Mitochondrial dynamics protein MIEF1|Mitochondrial dynamics protein of 51 kDa|Mitochondrial elongation factor 1|Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like (SMCR7-like protein)|MIEF1|MID51|SMCR7L
Background: Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa(also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.
-
分子量
- 49 kDa
-
基因ID
- 54471
-
UniProt
- Q9NQG6
抗原
-