SMC6 抗体
Quick Overview for SMC6 抗体 (ABIN7119188)
抗原
See all SMC6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SMC6 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- structural maintenance of chromosomes 6
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亚型
- IgG
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anti-SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6) (AA 1-110) antibody
SMC6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6) (AA 309-450) antibodySMC6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))
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别名
- SMC6
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背景
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Synonyms: Structural maintenance of chromosomes protein 6 (SMC protein 6, SMC-6, hSMC6)|SMC6|SMC6L1
Background: Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT(alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex(telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies(APBs). Required for recruitment of telomeres to PML nuclear bodies. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome(PubMed:26983541).
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分子量
- 130 kDa
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基因ID
- 79677
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UniProt
- Q96SB8
抗原
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