SRGAP2 抗体 (AA 780-940)
Quick Overview for SRGAP2 抗体 (AA 780-940) (ABIN7119134)
抗原
See all SRGAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 780-940
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原理
- SRGAP2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 780-940aa
Immunogen: SLIT-ROBO Rho GTPase activating protein 2
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亚型
- IgG
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anti-SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2) antibody
SRGAP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2) (AA 1040-1071), (C-Term) antibodySRGAP2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53245 unconjugated
anti-SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2) (AA 997-1030), (C-Term) antibodySRGAP2 适用: 人 WB 宿主: 兔 Polyclonal RB53246 unconjugated
anti-SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2) (Internal Region) antibodyVerified SRGAP2 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
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别名
- SRGAP2
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背景
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Synonyms: SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2)|Formin-binding protein 2|Rho GTPase-activating protein 34|SRGAP2|ARHGAP34|FNBP2|KIAA0456|SRGAP2A
Background: RAC1 GTPase activating protein(GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation, alters dendritic spine morphology and density and indirectly increases neuronal migration. It may have implications for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia.
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分子量
- 120-140 kDa
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基因ID
- 23380
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UniProt
- O75044
抗原
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