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SIRT5 抗体

The 兔 多克隆 anti-SIRT5 antibody is suitable to detect SIRT5 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IP.
产品编号 ABIN7119113
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SIRT5 抗体 (ABIN7119113)

抗原

See all SIRT5 抗体
SIRT5 (Sirtuin 5 (SIRT5))

适用

  • 92
  • 49
  • 29
  • 6
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 85
  • 13
  • 2
  • 2

克隆类型

  • 81
  • 21
多克隆

标记

  • 49
  • 15
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT5 antibody is un-conjugated

应用范围

  • 77
  • 33
  • 31
  • 21
  • 13
  • 10
  • 7
  • 6
  • 6
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • 原理

    SIRT5 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    sirtuin(silent mating type information regulation 2 homolog) 5

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:1000, IP: 1:500-1:1000, IF: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    SIRT5 (Sirtuin 5 (SIRT5))

    别名

    SIRT5

    背景

    Synonyms: NAD-dependent protein deacylase sirtuin-5, mitochondrial|Regulatory protein SIR2 homolog 5|SIR2-like protein 5|SIRT5|SIR2L5

    Background: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins(PubMed:21908771, PubMed:22076378, PubMed:24703693). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting(PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species(PubMed:24140062). Modulates ketogenesis through the desuccinylation and activation of HMGCS2(By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c(CYCS) and a number of other proteins in vitro such as UOX.

    分子量

    33 kDa

    UniProt

    Q9NXA8

    途径

    SARS-CoV-2 Protein Interactome
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