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SIRT5 抗体

SIRT5 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7119113
发货至: 中国
  • 抗原 See all SIRT5 抗体
    SIRT5 (Sirtuin 5 (SIRT5))
    适用
    • 89
    • 49
    • 28
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 83
    • 11
    • 2
    • 2
    克隆类型
    • 79
    • 19
    多克隆
    标记
    • 45
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRT5 antibody is un-conjugated
    应用范围
    • 76
    • 35
    • 31
    • 20
    • 13
    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    sirtuin(silent mating type information regulation 2 homolog) 5
    亚型
    IgG
    Top Product
    Discover our top product SIRT5 Primary Antibody
  • 应用备注
    WB: 1:500-1:1000, IP: 1:500-1:1000, IF: 1:50-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    SIRT5 (Sirtuin 5 (SIRT5))
    别名
    SIRT5 (SIRT5 产品)
    背景
    Synonyms:FLJ36950, SIR2 like protein 5, SIR2L5, SIRT5 Background:NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins(PubMed:21908771, PubMed:22076378, PubMed:24703693). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting(PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species(PubMed:24140062). Modulates ketogenesis through the desuccinylation and activation of HMGCS2(By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c(CYCS) and a number of other proteins in vitro such as UOX.
    分子量
    33 kDa
    UniProt
    Q9NXA8
    途径
    SARS-CoV-2 Protein Interactome
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