SH3PXD2A
适用: 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
Cy7
应用备注
WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
限制
仅限研究用
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
有效期
12 months
抗原
SH3PXD2A
(SH3 and PX Domains 2A (SH3PXD2A))
别名
SH3PXD2A
背景
Synonyms:FISH, KIAA0418, SH3MD1, TKS5 Background:Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases(ADAMs), NADPH oxidases(NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1-or NOX3-dependent reactive oxygen species(ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.