SH3PXD2A 抗体 (AA 385-533)
Quick Overview for SH3PXD2A 抗体 (AA 385-533) (ABIN7119018)
抗原
See all SH3PXD2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 385-533
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原理
- SH3PXD2A antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 385-533aa
Immunogen: SH3 and PX domains 2A
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亚型
- IgG
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anti-SH3 and PX Domains 2A (SH3PXD2A) antibody
SH3PXD2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SH3 and PX Domains 2A (SH3PXD2A) (N-Term) antibodySH3PXD2A 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SH3 and PX Domains 2A (SH3PXD2A) (AA 1-1105) antibodySH3PXD2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
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别名
- SH3PXD2A
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背景
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Synonyms: SH3 and PX domain-containing protein 2A|Adapter protein TKS5|Five SH3 domain-containing protein|SH3 multiple domains protein 1|Tyrosine kinase substrate with five SH3 domains|SH3PXD2A|FISH|KIAA0418|SH3MD1|TKS5
Background: Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases(ADAMs), NADPH oxidases(NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1-or NOX3-dependent reactive oxygen species(ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.
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分子量
- 140 kDa
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基因ID
- 9644
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UniProt
- Q5TCZ1
抗原
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