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SETD1B 抗体 (AA 350-459)

The 兔 多克隆 anti-SETD1B antibody is suitable to detect SETD1B in samples from 人 和 小鼠. It has been validated for WB, ELISA, IHC, IF 和 IP.
产品编号 ABIN7118990
发货至: 中国
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Quick Overview for SETD1B 抗体 (AA 350-459) (ABIN7118990)

抗原

See all SETD1B 抗体
SETD1B (SET Domain Containing 1B (SETD1B))

适用

  • 6
  • 4
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 7

克隆类型

  • 7
多克隆

标记

  • 7
This SETD1B antibody is un-conjugated

应用范围

  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    AA 350-459

    原理

    SETD1B antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: peptide(350-459aa)

    Immunogen: SET domain containing 1B

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    SETD1B (SET Domain Containing 1B (SETD1B))

    别名

    SETD1B

    背景

    Synonyms: Histone-lysine N-methyltransferase SETD1B|Lysine N-methyltransferase 2G|SET domain-containing protein 1B (hSET1B)|SETD1B|KIAA1076|KMT2G|SET1B

    Background: Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase(HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.

    分子量

    260 kDa

    基因ID

    23067

    UniProt

    Q9UPS6
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