SETD1B 抗体 (AA 350-459)
Quick Overview for SETD1B 抗体 (AA 350-459) (ABIN7118990)
抗原
See all SETD1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-459
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原理
- SETD1B antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: peptide(350-459aa)
Immunogen: SET domain containing 1B
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亚型
- IgG
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应用备注
- WB: 1:200-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SETD1B (SET Domain Containing 1B (SETD1B))
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别名
- SETD1B
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背景
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Synonyms: Histone-lysine N-methyltransferase SETD1B|Lysine N-methyltransferase 2G|SET domain-containing protein 1B (hSET1B)|SETD1B|KIAA1076|KMT2G|SET1B
Background: Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase(HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.
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分子量
- 260 kDa
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基因ID
- 23067
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UniProt
- Q9UPS6
抗原
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