SERPINC1 抗体 (AA 1-259)
Quick Overview for SERPINC1 抗体 (AA 1-259) (ABIN7118893)
抗原
See all SERPINC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-259
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原理
- SERPINC1 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-259aa
Immunogen: serpin peptidase inhibitor, clade C(antithrombin), member 1
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亚型
- IgG1
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应用备注
- WB: 1:500-1:5000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
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别名
- SERPINC1
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背景
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Synonyms: Antithrombin-III (ATIII)|Serpin C1|SERPINC1|AT3
Background: SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
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分子量
- 53 kDa
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基因ID
- 462
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UniProt
- P01008
抗原
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