SAFB 抗体
Quick Overview for SAFB 抗体 (ABIN7118797)
抗原
See all SAFB 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SAFB antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- scaffold attachment factor B
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SAFB (Scaffold Attachment Factor B (SAFB))
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别名
- SAFB
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背景
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Synonyms: Scaffold attachment factor B1 (SAF-B, SAF-B1)|HSP27 estrogen response element-TATA box-binding protein (HSP27 ERE-TATA-binding protein)|SAFB|HAP|HET|SAFB1
Background: Binds to scaffold/matrix attachment region(S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex(consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing(By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter(By similarity). Can inhibit cell proliferation.
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分子量
- 150 kDa
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基因ID
- 6294
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UniProt
- Q15424
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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