CHBL2 antibody, DCIP antibody, HDDC1 antibody, MOP-5 antibody, SBBI88 antibody, si:dkeyp-44b8.8 antibody, E330031J07Rik antibody, Mg11 antibody, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 antibody, SAM domain and HD domain 1 antibody, SAM domain and HD domain, 1 antibody, SAMHD1 antibody, samhd1 antibody, Samhd1 antibody
背景
Synonyms:MOP5 Background:Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.