SAMHD1 抗体
Quick Overview for SAMHD1 抗体 (ABIN7118779)
抗原
See all SAMHD1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SAMHD1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- SAM domain and HD domain 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
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别名
- SAMHD1
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背景
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Synonyms: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase)|Dendritic cell-derived IFNG-induced protein (DCIP)|Monocyte protein 5 (MOP-5)|SAM domain and HD domain-containing protein 1 (hSAMHD1)|SAMHD1|MOP5
Background: Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
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分子量
- 64-72 kDa
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基因ID
- 25939
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UniProt
- Q9Y3Z3
抗原
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