RBPMS 抗体
Quick Overview for RBPMS 抗体 (ABIN7118698)
抗原
See all RBPMS 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RBPMS antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- RNA binding protein with multiple splicing
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))
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别名
- RBPMS
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背景
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Synonyms: RNA-binding protein with multiple splicing (RBP-MS)|Heart and RRM expressed sequence (Hermes)|RBPMS|HERMES
Background: Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins(PubMed:26347403). Binds to poly(A) RNA(PubMed:17099224, PubMed:26347403).
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分子量
- 28-30 kDa
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基因ID
- 11030
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UniProt
- Q93062
抗原
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