RBM25 抗体
This anti-RBM25 antibody is a 兔 多克隆 antibody detecting RBM25 in WB, ELISA 和 IHC. Suitable for 小鼠 和 人.
Quick Overview for RBM25 抗体 (ABIN7118681)
抗原
See all RBM25 抗体
RBM25
(RNA Binding Motif Protein 25 (RBM25))
适用
小鼠, 人
宿主
兔
克隆类型
多克隆
标记
This RBM25 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- RNA binding motif protein 25
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亚型
- IgG
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anti-RNA Binding Motif Protein 25 (RBM25) (AA 614-843) antibody
RBM25 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 25 (RBM25) (AA 285-334) antibodyRBM25 适用: 小鼠, 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- RBM25 (RNA Binding Motif Protein 25 (RBM25))
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别名
- RBM25
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背景
- Synonyms:fSAP94, NET52, Protein S164, RBM25, RED120, RNA binding motif protein 25, RNA binding protein 25, RNPC7, S164 Background:RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site(5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.
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分子量
- 110-120 kDa
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基因ID
- 58517
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UniProt
- P49756
抗原
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