RBM14 抗体
Quick Overview for RBM14 抗体 (ABIN7118671)
抗原
See all RBM14 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RBM14 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- RNA binding motif protein 14
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RBM14 (RNA Binding Motif Protein 14 (RBM14))
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别名
- RBM14
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背景
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Synonyms: RNA-binding protein 14|Paraspeckle protein 2 (PSP2)|RNA-binding motif protein 14|RRM-containing coactivator activator/modulator|Synaptotagmin-interacting protein (SYT-interacting protein)|RBM14|SIP
Background: Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1(PubMed:11443112). Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex(which can induce the formation of aberrant centriolar protein complexes) by interfering with the interaction of STIL with CENPJ(PubMed:25385835).
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分子量
- 70-75 kDa
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基因ID
- 10432
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UniProt
- Q96PK6
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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