RLIM 抗体
Our Local Distributor
北京 101111
Quick Overview for RLIM 抗体 (ABIN7118663)
抗原
See all RLIM 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- RLIM antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- ring finger protein, LIM domain interacting
-
亚型
- IgG
-
-
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 1-83) antibody
RLIM 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 199-227) antibodyRLIM 适用: 人 WB 宿主: 兔 Polyclonal RB42228 unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 1-624) antibodyRLIM 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 532-581) antibodyRLIM 适用: 人, 犬, 马, Cow, 兔, Pig, Bat, 小鸡, Hamster, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (C-Term) antibodyRLIM 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, Pig, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 550-600) antibodyRLIM 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 1-83) antibodyRLIM 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 1-624) antibodyRLIM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (N-Term) antibodyRLIM 适用: 人, 犬, 马, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))
-
别名
- RLIM
-
背景
-
Synonyms: E3 ubiquitin-protein ligase RLIM|LIM domain-interacting RING finger protein|RING finger LIM domain-binding protein (R-LIM)|RING finger protein 12|RING-type E3 ubiquitin transferase RLIM|Renal carcinoma antigen NY-REN-43|RLIM|RNF12
Background: E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1. By targeting ZFP42 for degradation, acts as an activator of random inactivation of X chromosome in the embryo, a stochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes in somatic cells of female placental mammals.
-
分子量
- 75 kDa
-
基因ID
- 51132
-
UniProt
- Q9NVW2
抗原
-
