RNF7 抗体
Quick Overview for RNF7 抗体 (ABIN7118661)
抗原
See all RNF7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- RNF7 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- ring finger protein 7
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- RNF7 (Ring Finger Protein 7 (RNF7))
-
别名
- RNF7
-
背景
-
Synonyms: RING-box protein 2 (Rbx2)|CKII beta-binding protein 1 (CKBBP1)|RING finger protein 7|Regulator of cullins 2|Sensitive to apoptosis gene protein|RNF7|RBX2|ROC2|SAG
Background: Probable component of the SCF(SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
-
分子量
- 13 kDa
-
基因ID
- 9616
-
UniProt
- Q9UBF6
-
途径
- Positive Regulation of Endopeptidase Activity
抗原
-