RNF6 抗体
Quick Overview for RNF6 抗体 (ABIN7118660)
抗原
See all RNF6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RNF6 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ring finger protein(C3H2C3 type) 6
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RNF6 (RING Finger Protein 6 (RNF6))
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别名
- RNF6
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背景
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Synonyms: E3 ubiquitin-protein ligase RNF6|RNF6|SPG2
Background: E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
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分子量
- 78 kDa
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基因ID
- 6049
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UniProt
- Q9Y252
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size
抗原
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