RNF212 抗体
Quick Overview for RNF212 抗体 (ABIN7118647)
抗原
See all RNF212 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RNF212 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ring finger protein 212
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RNF212 (Ring Finger Protein 212 (RNF212))
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别名
- RNF212
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背景
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Synonyms: Probable E3 SUMO-protein ligase RNF212|Probable E3 SUMO-protein transferase RNF212|RING finger protein 212|RNF212
Background: SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins(MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination(By similarity).
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分子量
- 22 kDa
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基因ID
- 285498
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UniProt
- Q495C1
抗原
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