RING1 抗体
Quick Overview for RING1 抗体 (ABIN7118632)
抗原
See all RING1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ring finger protein 1
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亚型
- IgG
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anti-Ring Finger Protein 1 (RING1) (AA 79-263) antibody
RING1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8C12F4 unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 79-263) antibodyRING1 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 8E8A2 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B3 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 401-630) antibodyRING1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A6 unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- RING1 (Ring Finger Protein 1 (RING1))
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别名
- RING1
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背景
- Synonyms:RNF1 Background:Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity.
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分子量
- 50 kDa
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基因ID
- 6015
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UniProt
- Q06587
抗原
-
