RHBDD1 抗体
Quick Overview for RHBDD1 抗体 (ABIN7118505)
抗原
See all RHBDD1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RHBDD1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- rhomboid domain containing 1
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亚型
- IgG
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anti-Rhomboid Domain Containing 1 (RHBDD1) (AA 206-315) antibody
RHBDD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Rhomboid Domain Containing 1 (RHBDD1) antibodyRHBDD1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Rhomboid Domain Containing 1 (RHBDD1) (C-Term) antibodyRHBDD1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
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别名
- RHBDD1
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背景
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Synonyms: Rhomboid-related protein 4 (RRP4)|Rhomboid domain-containing protein 1|Rhomboid-like protein 4|RHBDD1|RHBDL4
Background: Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation(ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum(ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion, inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis, modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis, inhibits apoptotic activity in spermatogonia.
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分子量
- 36 kDa
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基因ID
- 84236
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UniProt
- Q8TEB9
抗原
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