ARHGEF4 抗体
Quick Overview for ARHGEF4 抗体 (ABIN7118493)
抗原
See all ARHGEF4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ARHGEF4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Rho guanine nucleotide exchange factor(GEF) 4
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亚型
- IgG
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (N-Term) antibody
ARHGEF4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (N-Term) antibodyVerified ARHGEF4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 143-271) antibodyARHGEF4 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal ARHGEF-08 unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 143-271) antibody (PE)ARHGEF4 适用: 人 ICFC 宿主: 小鼠 Monoclonal ARHGEF-08 PE
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 1-100) antibodyARHGEF4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (Internal Region) antibodyARHGEF4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 51-100) antibodyARHGEF4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
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别名
- ARHGEF4
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背景
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Synonyms: Rho guanine nucleotide exchange factor 4|APC-stimulated guanine nucleotide exchange factor 1 (Asef, Asef1)|ARHGEF4|KIAA1112
Background: Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
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分子量
- 72 kDa
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基因ID
- 50649
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UniProt
- Q9NR80
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途径
- Neurotrophin Signaling Pathway
抗原
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