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Retinoid X Receptor alpha 抗体

This anti-Retinoid X Receptor alpha antibody is a 兔 多克隆 antibody detecting Retinoid X Receptor alpha in WB, ELISA, IHC, IP 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7118448
发货至: 中国

Quick Overview for Retinoid X Receptor alpha 抗体 (ABIN7118448)

抗原

See all Retinoid X Receptor alpha (RXRA) 抗体
Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Retinoid X Receptor alpha antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    retinoid X receptor, alpha

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

    别名

    RXRA

    背景

    Synonyms:FLJ00280, FLJ00318, FLJ16020, FLJ16733, NR2B1, Retinoid X receptor alpha, retinoid X receptor, alpha, RXRA Background:Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements(RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. The RXR/RAR heterodimers bind to the retinoic acid response elements(RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXRA/PPARA heterodimer is required for PPARA transcriptional activity on fatty acid oxidation genes such as ACOX1 and the P450 system genes.

    分子量

    51 kDa

    基因ID

    6256

    UniProt

    P19793

    途径

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C
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