RPE65 抗体
Quick Overview for RPE65 抗体 (ABIN7118420)
抗原
See all RPE65 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RPE65 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- retinal pigment epithelium-specific protein 65kDa
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
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别名
- RPE65
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背景
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Synonyms: Retinoid isomerohydrolase|All-trans-retinyl-palmitate hydrolase|Lutein isomerase|Meso-zeaxanthin isomerase|Retinal pigment epithelium-specific 65 kDa protein|Retinol isomerase|RPE65
Background: Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A(all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH(isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.
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分子量
- 65 kDa, 61 kDa
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基因ID
- 6121
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UniProt
- Q16518
抗原
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