Reticulon 3 抗体
Quick Overview for Reticulon 3 抗体 (ABIN7118415)
抗原
See all Reticulon 3 (RTN3) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RTN3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- reticulon 3
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Reticulon 3 (RTN3)
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别名
- RTN3
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背景
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Synonyms: Reticulon-3|Homolog of ASY protein (HAP)|Neuroendocrine-specific protein-like 2 (NSP-like protein 2)|Neuroendocrine-specific protein-like II (NSP-like protein II, NSPLII)|RTN3|ASYIP|NSPL2
Background: May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules(PubMed:25612671).
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分子量
- 24 kDa, 113 kDa
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基因ID
- 10313
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UniProt
- O95197
抗原
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