TRIM27 抗体
Quick Overview for TRIM27 抗体 (ABIN7118412)
抗原
See all TRIM27 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- tripartite motif-containing 27
-
亚型
- IgG
-
-
anti-Tripartite Motif Containing 27 (TRIM27) (AA 1-200) antibody
TRIM27 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) antibodyTRIM27 适用: 人 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) (AA 214-513) antibodyTRIM27 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) antibodyTRIM27 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) antibodyTRIM27 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) antibodyTRIM27 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) (AA 141-190) antibodyTRIM27 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) (AA 151-200) antibodyTRIM27 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) (Middle Region) antibodyTRIM27 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
有效期
- 12 months
-
-
- TRIM27 (Tripartite Motif Containing 27 (TRIM27))
-
别名
- TRIM27
-
背景
- Synonyms:Ret finger protein, RFP, RING finger protein 76, RNF76, TRIM27, tripartite motif containing 27, Zinc finger protein RFP Background:E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity, mediates the formation of 'Lys-48'-linked polyubiquitin chains, the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASH1, leading to promote endosomal F-actin assembly(PubMed:23452853). Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA.
-
分子量
- 58 kDa
-
基因ID
- 5987
-
UniProt
- P14373
抗原
-
