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RFX3 抗体

This anti-RFX3 antibody is a 兔 多克隆 antibody detecting RFX3 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7118388
发货至: 中国

Quick Overview for RFX3 抗体 (ABIN7118388)

抗原

See all RFX3 抗体
RFX3 (Regulatory Factor X 3 (RFX3))

适用

  • 27
  • 7
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 24
  • 3

克隆类型

  • 26
  • 1
多克隆

标记

  • 18
  • 3
  • 2
  • 2
  • 1
  • 1
This RFX3 antibody is un-conjugated

应用范围

  • 22
  • 15
  • 5
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    regulatory factor X, 3(influences HLA class II expression)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    RFX3 (Regulatory Factor X 3 (RFX3))

    别名

    RFX3

    背景

    Synonyms: Background:Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly(DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility(DNAH11, DNAH9 and DNAH5)(By similarity). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP(polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes(PubMed:20148032). Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells(PubMed:12411430).

    分子量

    70-79 kDa

    基因ID

    5991

    UniProt

    P48380
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