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RFX3 抗体 (C-Term)

RFX3 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264716
发货至: 中国
  • 抗原 See all RFX3 抗体
    RFX3 (Regulatory Factor X 3 (RFX3))
    抗原表位
    • 10
    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 39
    • 14
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠
    宿主
    • 36
    • 3
    克隆类型
    • 38
    • 1
    多克隆
    标记
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RFX3 antibody is un-conjugated
    应用范围
    • 27
    • 19
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    RFX3 Antibody detects endogenous levels of total RFX3.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RFX3, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    RFX3 (Regulatory Factor X 3 (RFX3))
    别名
    RFX3 (RFX3 产品)
    别名
    ba32f11.1 antibody, C230093O12Rik antibody, MRFX3 antibody, zgc:153245 antibody, regulatory factor X3 antibody, regulatory factor X, 3 (influences HLA class II expression) antibody, Rfx3 antibody, rfx3 antibody, RFX3 antibody
    背景

    Description: Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5) (By similarity). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes (PubMed:20148032). Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells (PubMed:12411430).

    Gene: RFX3

    分子量
    84kDa
    基因ID
    5991
    UniProt
    P48380
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