RTEL1 抗体
Quick Overview for RTEL1 抗体 (ABIN7118387)
抗原
See all RTEL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- RTEL1 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- regulator of telomere elongation helicase 1
-
亚型
- IgG
-
-
anti-Regulator of Telomere Elongation Helicase 1 (RTEL1) (AA 975-1219) antibody
RTEL1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Telomere Elongation Helicase 1 (RTEL1) (AA 651-756) antibodyRTEL1 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Telomere Elongation Helicase 1 (RTEL1) antibodyRTEL1 适用: 人, 小鼠 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Telomere Elongation Helicase 1 (RTEL1) (N-Term) antibodyRTEL1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))
-
别名
- RTEL1
-
背景
-
Synonyms: Regulator of telomere elongation helicase 1|Novel helicase-like|RTEL1|C20orf41|KIAA1088|NHL
Background: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing(SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
-
分子量
- 133 kDa
-
基因ID
- 51750
-
UniProt
- Q9NZ71
抗原
-
