RCC1 抗体
Quick Overview for RCC1 抗体 (ABIN7118374)
抗原
See all RCC1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RCC1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- regulator of chromosome condensation 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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别名
- RCC1
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背景
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Synonyms: Regulator of chromosome condensation|Cell cycle regulatory protein|Chromosome condensation protein 1|RCC1|CHC1
Background: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex(together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
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分子量
- 50 kDa
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基因ID
- 1104
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UniProt
- P18754
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途径
- Chromatin Binding, Protein targeting to Nucleus
抗原
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