RECQL5 抗体
Quick Overview for RECQL5 抗体 (ABIN7118358)
抗原
See all RECQL5 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RECQL5 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- RecQ protein-like 5
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亚型
- IgG
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anti-RecQ Protein-Like 5 (RECQL5) (AA 1-435) antibody
RECQL5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RecQ Protein-Like 5 (RECQL5) (AA 431-480) antibodyRECQL5 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RECQL5 (RecQ Protein-Like 5 (RECQL5))
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别名
- RECQL5
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背景
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Synonyms: ATP-dependent DNA helicase Q5|DNA helicase, RecQ-like type 5 (RecQ5)|RecQ protein-like 5|RECQL5|RECQ5
Background: Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.
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分子量
- 50-60 kDa
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基因ID
- 9400
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UniProt
- O94762
抗原
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