RECQL5
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
FITC
应用备注
WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
限制
仅限研究用
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
有效期
12 months
抗原
RECQL5
(RecQ Protein-Like 5 (RECQL5))
别名
RECQL5
背景
Synonyms:RECQL5, DNA helicase, RecQ like type 5, ATP dependent DNA helicase Q5, RecQ protein like 5, RECQ5 Background:Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.