RAB7A 抗体
Quick Overview for RAB7A 抗体 (ABIN7118232)
抗原
See all RAB7A 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- RAB7A, member RAS oncogene family
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亚型
- IgG
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anti-RAB7A, Member RAS Oncogene Family (RAB7A) (C-Term) antibody
RAB7A 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, 猴, 兔, Cat, 驴, 山羊, 豚鼠, Hamster, 马, Pig, Avian, 绵羊 WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 176-204), (C-Term) antibodyRAB7A 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21394 unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 101-207) antibodyRAB7A 适用: 人, 小鼠 WB, ELISA, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 176-204) antibodyRAB7A 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 110-177) antibodyRAB7A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) antibodyRAB7A 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 1-207) antibodyRAB7A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (C-Term) antibodyRAB7A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (C-Term) antibodyRAB7A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) antibodyRAB7A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
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别名
- RAB7A
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背景
- Synonyms:PRO2706, RAB7, RAB7A, Ras related protein Rab 7a Background:Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth-factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism. Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced phagosomes(or vacuoles) and autophagosomes. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. Microbial pathogens possess survival strategies governed by RAB7A, sometimes by employing RAB7A function(e.g. Salmonella) and sometimes by excluding RAB7A function(e.g. Mycobacterium). In concert with RAC1, plays a role in regulating the formation of RBs(ruffled borders) in osteoclasts. Controls the endosomal trafficking and neurite outgrowth signaling of NTRK1/TRKA(PubMed:11179213, PubMed:12944476, PubMed:14617358, PubMed:20028791, PubMed:21255211). Regulates the endocytic trafficking of the EGF-EGFR complex by regulating its lysosomal degradation. Involved in the ADRB2-stimulated lipolysis through lipophagy, a cytosolic lipase-independent autophagic pathway(By similarity). Required for the exosomal release of SDCBP, CD63 and syndecan(PubMed:22660413).
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分子量
- 23 kDa
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基因ID
- 7879
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UniProt
- P51149
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途径
- EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
抗原
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