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RSPO2 抗体

This anti-RSPO2 antibody is a 兔 多克隆 antibody detecting RSPO2 in WB, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7118172
发货至: 中国

Quick Overview for RSPO2 抗体 (ABIN7118172)

抗原

See all RSPO2 抗体
RSPO2 (R-Spondin 2 (RSPO2))

适用

人, 小鼠, 大鼠

宿主

  • 13

克隆类型

  • 13
多克隆

标记

  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
This RSPO2 antibody is un-conjugated

应用范围

  • 13
  • 11
  • 11
  • 11
  • 2
Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    R-spondin 2 homolog

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IP: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    RSPO2 (R-Spondin 2 (RSPO2))

    别名

    RSPO2

    背景

    Synonyms:CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 Background:Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.

    分子量

    33 kDa

    基因ID

    340419

    UniProt

    Q6UXX9
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