RSPO2 抗体 (AA 22-243)
Quick Overview for RSPO2 抗体 (AA 22-243) (ABIN7118172)
抗原
See all RSPO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-243
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原理
- RSPO2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 22-243aa
Immunogen: R-spondin 2 homolog
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亚型
- IgG
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anti-R-Spondin 2 (RSPO2) (AA 190-218), (C-Term) antibody
RSPO2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26400 unconjugated
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应用备注
- WB: 1:500-1:3000, IP: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RSPO2 (R-Spondin 2 (RSPO2))
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别名
- RSPO2
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背景
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Synonyms: R-spondin-2|Roof plate-specific spondin-2 (hRspo2)|RSPO2
Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.
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分子量
- 33 kDa
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基因ID
- 340419
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UniProt
- Q6UXX9
抗原
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