PTPMT1 抗体
Quick Overview for PTPMT1 抗体 (ABIN7118052)
抗原
See all PTPMT1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PTPMT1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- protein tyrosine phosphatase, mitochondrial 1
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亚型
- IgG
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应用备注
- WB: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))
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别名
- PTPMT1
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背景
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Synonyms: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1|PTEN-like phosphatase|Phosphoinositide lipid phosphatase|Protein-tyrosine phosphatase mitochondrial 1|PTPMT1|MOSP|PLIP
Background: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate(PGP) to phosphatidylglycerol(PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells(By similarity).
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分子量
- 21-23 kDa
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基因ID
- 114971
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UniProt
- Q8WUK0
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途径
- Inositol Metabolic Process
抗原
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