PPM1B 抗体
Quick Overview for PPM1B 抗体 (ABIN7118038)
抗原
See all PPM1B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- PPM1B antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- protein phosphatase 1B(formerly 2C), magnesium-dependent, beta isoform
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
-
别名
- PPM1B
-
背景
-
Synonyms: Protein phosphatase 1B|Protein phosphatase 2C isoform beta (PP2C-beta)|PPM1B|PP2CB
Background: Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
-
分子量
- 50-53 kDa
-
基因ID
- 5495
-
UniProt
- O75688
抗原
-