PPP1R9B 抗体
Quick Overview for PPP1R9B 抗体 (ABIN7118007)
抗原
See all PPP1R9B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PPP1R9B antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- protein phosphatase 1, regulatory(inhibitor) subunit 9B
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亚型
- IgG
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anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) (C-Term) antibody
PPP1R9B 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) (AA 708-817) antibodyPPP1R9B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) (AA 358-460) antibodyPPP1R9B 适用: 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) antibodyPPP1R9B 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PPP1R9B (Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B))
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别名
- PPP1R9B
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背景
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Synonyms: Neurabin-2|Neurabin-II|Protein phosphatase 1 regulatory subunit 9B|Spinophilin|PPP1R9B|PPP1R6
Background: Seems to act as a scaffold protein in multiple signaling pathways. Modulates excitatory synaptic transmission and dendritic spine morphology. Binds to actin filaments(F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction. Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AMPA-type and NMDA-type glutamate receptors. Plays a role in regulation of G-protein coupled receptor signaling, including dopamine D2 receptors and alpha-adrenergic receptors. May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton. Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling. May confer to Rac signaling specificity by binding to both, RacGEFs and Rac effector proteins. Probably regulates p70 S6 kinase activity by forming a complex with TIAM1(By similarity). Required for hepatocyte growth factor(HGF)-induced cell migration.
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分子量
- 120-130 kDa
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基因ID
- 84687
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UniProt
- Q96SB3
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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