PPP1CC 抗体
Quick Overview for PPP1CC 抗体 (ABIN7117989)
抗原
See all PPP1CC 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PPP1CC antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- protein phosphatase 1, catalytic subunit, gamma isoform
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亚型
- IgG
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anti-Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC) (Center) antibody
PPP1CC 适用: 人, 小鼠 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC) (AA 1-323) antibodyPPP1CC 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC) (AA 151-323), (Catalytic Subunit) antibodyPPP1CC 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC) antibodyPPP1CC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC) (AA 1-323) antibodyPPP1CC 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC) (AA 1-323) antibodyPPP1CC 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))
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别名
- PPP1CC
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背景
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Synonyms: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G)|Protein phosphatase 1C catalytic subunit|PPP1CC
Background: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1(PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells(Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective(PubMed:23396208).
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分子量
- 35 kDa
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基因ID
- 5501
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UniProt
- P36873
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途径
- Cellular Glucan Metabolic Process, Lipid Metabolism
抗原
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