POFUT2 抗体
Quick Overview for POFUT2 抗体 (ABIN7117982)
抗原
See all POFUT2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- POFUT2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- protein O-fucosyltransferase 2
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))
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别名
- POFUT2
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背景
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Synonyms: GDP-fucose protein O-fucosyltransferase 2|Peptide-O-fucosyltransferase 2 (O-FucT-2)|POFUT2|C21orf80|FUT13|KIAA0958
Background: Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin(TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition(EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm(By similarity). Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.
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分子量
- 49 kDa, 50 kDa
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基因ID
- 23275
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UniProt
- Q9Y2G5
抗原
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