PKMYT1 抗体
Quick Overview for PKMYT1 抗体 (ABIN7117978)
抗原
See all PKMYT1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PKMYT1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- protein kinase, membrane associated tyrosine/threonine 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))
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别名
- PKMYT1
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背景
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Synonyms: Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase|Myt1 kinase|PKMYT1|MYT1
Background: Acts as a negative regulator of entry into mitosis(G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
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分子量
- 55 kDa
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基因ID
- 9088
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UniProt
- Q99640
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途径
- Mitotic G1-G1/S Phases, M Phase
抗原
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