PKN2 抗体
Quick Overview for PKN2 抗体 (ABIN7117963)
抗原
See all PKN2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PKN2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- protein kinase N2
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亚型
- IgG
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anti-Protein Kinase N2 (PKN2) antibody
PKN2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Protein Kinase N2 (PKN2) (AA 580-679) antibodyPKN2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-Protein Kinase N2 (PKN2) antibodyPKN2 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N2 (PKN2) (AA 925-969) antibodyPKN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N2 (PKN2) (AA 67-312) antibodyPKN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N2 (PKN2) antibodyPKN2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Protein Kinase N2 (PKN2) (AA 108-141) antibodyPKN2 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB50147 unconjugated
anti-Protein Kinase N2 (PKN2) (AA 891-940) antibodyPKN2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N2 (PKN2) (AA 605-654) antibodyPKN2 适用: 人, Cow, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N2 (PKN2) (C-Term) antibodyPKN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PKN2 (Protein Kinase N2 (PKN2))
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别名
- PKN2
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背景
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Synonyms: Serine/threonine-protein kinase N2|PKN gamma|Protein kinase C-like 2|Protein-kinase C-related kinase 2|PKN2|PRK2|PRKCL2
Background: PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation. Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion. Inhibits Akt pro-survival-induced kinase activity. Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor(SRF). Phosphorylates HCV NS5B leading to stimulation of HCV RNA replication.
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分子量
- 130 kDa
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基因ID
- 5586
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UniProt
- Q16513
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途径
- Cell-Cell Junction Organization
抗原
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