PACSIN2 抗体
Quick Overview for PACSIN2 抗体 (ABIN7117946)
抗原
See all PACSIN2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PACSIN2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- protein kinase C and casein kinase substrate in neurons 2
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PACSIN2 (Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2))
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别名
- PACSIN2
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背景
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Synonyms: Protein kinase C and casein kinase substrate in neurons protein 2|Syndapin-2|Syndapin-II (SdpII)|PACSIN2
Background: Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
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分子量
- 60-65 kDa
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基因ID
- 11252
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UniProt
- Q9UNF0
抗原
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