PICK1 抗体
Quick Overview for PICK1 抗体 (ABIN7117943)
抗原
See all PICK1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PICK1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- protein interacting with PRKCA 1
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亚型
- IgG
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anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) antibody
PICK1 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-200) antibodyPICK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (Internal Region) antibodyVerified PICK1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 266-375) antibodyPICK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G5 unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 24-229) antibodyPICK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 260-360) antibodyPICK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (N-Term) antibodyPICK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 305-318), (Intracellular) antibodyPICK1 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 266-375) antibodyPICK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-415) antibodyPICK1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
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别名
- PICK1
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背景
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Synonyms: PRKCA-binding protein|Protein interacting with C kinase 1|Protein kinase C-alpha-binding protein|PICK1|PRKCABP
Background: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor(AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression(LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
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分子量
- 50-55 kDa
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基因ID
- 9463
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UniProt
- Q9NRD5
抗原
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