POT1 抗体
Quick Overview for POT1 抗体 (ABIN7117924)
抗原
See all POT1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- POT1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- POT1 protection of telomeres 1 homolog (S. pombe)
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- POT1 (Protection of Telomeres 1 (POT1))
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别名
- POT1
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背景
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Synonyms: Protection of telomeres protein 1 (hPot1)|POT1-like telomere end-binding protein|POT1
Background: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
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分子量
- 75 kDa
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基因ID
- 25913
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UniProt
- Q9NUX5
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途径
- Cell Division Cycle, Telomere Maintenance
抗原
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