PDCD6 抗体
Quick Overview for PDCD6 抗体 (ABIN7117800)
抗原
See all PDCD6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PDCD6 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- programmed cell death 6
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亚型
- IgG
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应用备注
- WB: 1:200 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PDCD6 (Programmed Cell Death 6 (PDCD6))
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别名
- PDCD6
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背景
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Synonyms: Programmed cell death protein 6|Apoptosis-linked gene 2 protein homolog (ALG-2)|PDCD6|ALG2
Background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.
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分子量
- 16 kDa
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基因ID
- 10016
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UniProt
- O75340
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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