Gastrin-Releasing Peptide 抗体 (AA 1-148)
Quick Overview for Gastrin-Releasing Peptide 抗体 (AA 1-148) (ABIN7117775)
抗原
See all Gastrin-Releasing Peptide (GRP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-148
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原理
- GRP antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-148aa
Immunogen: gastrin-releasing peptide
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Gastrin-Releasing Peptide (GRP)
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别名
- GRP
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背景
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Synonyms: Gastrin-releasing peptide (GRP)|Neuromedin-C Alternative names: GRP-10|GRP18-27|GRP
Background: Gastrin-releasing peptide, also known as GRP, is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, and its main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Its 148-amino acid preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27-amino acid gastrin-releasing peptide or the 10-amino acid neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate.
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分子量
- 16 kDa, 32 kDa
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基因ID
- 2922
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UniProt
- P07492
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途径
- Peptide Hormone Metabolism, Hormone Activity
抗原
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