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PBX1 抗体

PBX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7117746
发货至: 中国
  • 抗原 See all PBX1 抗体
    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
    适用
    • 23
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 15
    • 7
    • 1
    克隆类型
    • 17
    • 6
    多克隆
    标记
    • 19
    • 2
    • 1
    • 1
    This PBX1 antibody is un-conjugated
    应用范围
    • 17
    • 13
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    pre-B-cell leukemia homeobox 1
    亚型
    IgG
    Top Product
    Discover our top product PBX1 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
    别名
    PBX1 (PBX1 产品)
    别名
    fi29e01 antibody, pbx1b antibody, wu:fi29e01 antibody, zgc:55265 antibody, 2310056B04Rik antibody, AI848790 antibody, AU015730 antibody, D230003C07Rik antibody, Pbx-1 antibody, Pbx1a antibody, Pbx1b antibody, PBX1A antibody, Xpbx1 antibody, Xpbx1b antibody, PBX homeobox 1 antibody, pre-B-cell leukemia homeobox 1a antibody, pre B cell leukemia homeobox 1 antibody, pre-B-cell leukemia homeobox 1 S homeolog antibody, PBX1 antibody, pbx1a antibody, Pbx1 antibody, pbx1.S antibody
    背景
    Synonyms:PRL Background:Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the(1,19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex(PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with NKX2-5, it is required for spleen development through a mechanism that involves CDKN2B repression(By similarity).
    分子量
    52 kDa
    基因ID
    5087
    UniProt
    P40424
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