PBX1 抗体
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北京 101111
Quick Overview for PBX1 抗体 (ABIN7117746)
抗原
See all PBX1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PBX1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- pre-B-cell leukemia homeobox 1
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亚型
- IgG
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anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 213-321) antibody
PBX1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4A2 unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 315-430) antibodyPBX1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (Internal Region) antibodyVerified PBX1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 213-321) antibodyPBX1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 311-403) antibodyPBX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (N-Term) antibodyPBX1 适用: 人, 小鼠, 大鼠, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (Center) antibodyPBX1 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (N-Term) antibodyPBX1 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
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别名
- PBX1
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背景
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Synonyms: Pre-B-cell leukemia transcription factor 1|Homeobox protein PBX1|Homeobox protein PRL|PBX1|PRL
Background: Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the(1,19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex(PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with NKX2-5, it is required for spleen development through a mechanism that involves CDKN2B repression(By similarity).
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分子量
- 52 kDa
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基因ID
- 5087
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UniProt
- P40424
抗原
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