PUF60 抗体
Quick Overview for PUF60 抗体 (ABIN7117635)
抗原
See all PUF60 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PUF60 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- poly-U binding splicing factor 60KDa
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100, IP: 1:20 - 1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
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别名
- PUF60
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背景
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Synonyms: Poly(U)-binding-splicing factor PUF60|60 kDa poly(U)-binding-splicing factor|FUSE-binding protein-interacting repressor (FBP-interacting repressor)|Ro-binding protein 1 (RoBP1)|Siah-binding protein 1 (Siah-BP1)|PUF60|FIR|ROBPI|SIAHBP1
Background: This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 65 kDa
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基因ID
- 22827
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UniProt
- Q9UHX1
抗原
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