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PLCD4 抗体

The 兔 多克隆 anti-PLCD4 antibody (ABIN7117488) specifically detects PLCD4 in IHC 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7117488
发货至: 中国
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Quick Overview for PLCD4 抗体 (ABIN7117488)

抗原

See all PLCD4 抗体
PLCD4 (Phospholipase C, delta 4 (PLCD4))

适用

人, 小鼠, 大鼠

宿主

  • 14
  • 3

克隆类型

  • 15
  • 2
多克隆

标记

  • 13
  • 2
  • 1
  • 1
This PLCD4 antibody is un-conjugated

应用范围

  • 11
  • 7
  • 7
  • 4
  • 2
  • 2
  • 2
Immunohistochemistry (IHC), ELISA
  • 原理

    PLCD4 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    phospholipase C, delta 4

    亚型

    IgG
  • 应用备注

    IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    PLCD4 (Phospholipase C, delta 4 (PLCD4))

    别名

    PLCD4

    背景

    Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (hPLCD4)|Phosphoinositide phospholipase C-delta-4|Phospholipase C-delta-4 (PLC-delta-4)|PLCD4

    Background: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.

    基因ID

    84812

    UniProt

    Q9BRC7

    途径

    Inositol Metabolic Process
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