PLCD4 抗体
Quick Overview for PLCD4 抗体 (ABIN7117488)
抗原
See all PLCD4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PLCD4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- phospholipase C, delta 4
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亚型
- IgG
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anti-Phospholipase C, delta 4 (PLCD4) (AA 1-250) antibody
PLCD4 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C, delta 4 (PLCD4) (AA 18-127) antibodyPLCD4 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4D4 unconjugated
anti-Phospholipase C, delta 4 (PLCD4) (AA 1-762) antibodyPLCD4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C, delta 4 (PLCD4) (AA 1-290) antibodyPLCD4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C, delta 4 (PLCD4) (AA 1-762) antibodyPLCD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C, delta 4 (PLCD4) (AA 1-290) antibodyPLCD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PLCD4 (Phospholipase C, delta 4 (PLCD4))
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别名
- PLCD4
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背景
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Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (hPLCD4)|Phosphoinositide phospholipase C-delta-4|Phospholipase C-delta-4 (PLC-delta-4)|PLCD4
Background: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
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基因ID
- 84812
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UniProt
- Q9BRC7
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途径
- Inositol Metabolic Process
抗原
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